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Regulation of T cells by mTOR: The known knowns and the known unknowns

Mammalian/mechanistic target of rapamycin (mTOR) is emerging as an important integrator of environmental cues critical for the regulation of T cell activation, differentiation and function. Recent studies leveraging pharmacologic inhibition or T cell specific genetic deletion of signaling components...

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Detalhes bibliográficos
Publicado no:Trends Immunol
Main Authors: Pollizzi, Kristen N., Powell, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290883/
https://ncbi.nlm.nih.gov/pubmed/25522665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.11.005
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