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An Fc Domain Protein–Small Molecule Conjugate as an Enhanced Immunomodulator

[Image: see text] Proteins as well as small molecules have demonstrated success as therapeutic agents, but their pharmacologic properties sometimes fall short against particular drug targets. Although the adenosine 2a receptor (A(2A)R) has been identified as a promising target for immunotherapy, sma...

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Detalhes bibliográficos
Main Authors: Chiang, Meng-Jung, Holbert, Marc A., Kalin, Jay H., Ahn, Young-Hoon, Giddens, John, Amin, Mohammed N., Taylor, Martin S., Collins, Samuel L., Chan-Li, Yee, Waickman, Adam, Hsiao, Po-Yuan, Bolduc, David, Leahy, Daniel J., Horton, Maureen R., Wang, Lai-Xi, Powell, Jonathan D., Cole, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954559/
https://ncbi.nlm.nih.gov/pubmed/24533830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5006674
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