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Hyaluronan Fragments Promote Inflammation by Down-Regulating the Anti-inflammatory A2a Receptor

The tissue microenvironment plays a critical role in regulating inflammation. Chronic inflammation leads to an influx of inflammatory cells and mediators, extracellular matrix turnover, and increased extracellular adenosine. Low molecular weight (LMW) fragments of hyaluronan (HA), a matrix component...

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Detalhes bibliográficos
Main Authors: Collins, Samuel L., Black, Katharine E., Chan-Li, Yee, Ahn, Young-Hoon, Cole, Philip A., Powell, Jonathan D., Horton, Maureen R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208614/
https://ncbi.nlm.nih.gov/pubmed/21257926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0387OC
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