Hyaluronan fragments induce IFNβ via a novel TLR4-TRIF-TBK1-IRF3-dependent pathway

BACKGROUND: The extracellular matrix plays a critical role in insuring tissue integrity and water homeostasis. However, breakdown products of the extracellular matrix have emerged as endogenous danger signals, designed to rapidly activate the immune system against a potential pathogen breach. Type I...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Black, Katharine E, Collins, Samuel L, Hagan, Robert S, Hamblin, Mark J, Chan-Li, Yee, Hallowell, Robert W, Powell, Jonathan D, Horton, Maureen R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682892/
https://ncbi.nlm.nih.gov/pubmed/23721397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-10-23
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados