Hyaluronan Fragments Promote Inflammation by Down-Regulating the Anti-inflammatory A2a Receptor

The tissue microenvironment plays a critical role in regulating inflammation. Chronic inflammation leads to an influx of inflammatory cells and mediators, extracellular matrix turnover, and increased extracellular adenosine. Low molecular weight (LMW) fragments of hyaluronan (HA), a matrix component...

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Hlavní autoři: Collins, Samuel L., Black, Katharine E., Chan-Li, Yee, Ahn, Young-Hoon, Cole, Philip A., Powell, Jonathan D., Horton, Maureen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2011
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208614/
https://ncbi.nlm.nih.gov/pubmed/21257926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0387OC
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