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mTORC1 and mTORC2 selectively regulate CD8(+) T cell differentiation
Activation of mTOR-dependent pathways regulates the specification and differentiation of CD4(+) T effector cell subsets. Herein, we show that mTOR complex 1 (mTORC1) and mTORC2 have distinct roles in the generation of CD8(+) T cell effector and memory populations. Evaluation of mice with a T cell–sp...
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| Yayımlandı: | J Clin Invest |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463194/ https://ncbi.nlm.nih.gov/pubmed/25893604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77746 |
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