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mTORC1 signaling regulates the generation and function of central and effector FoxP3(+) regulatory T cells (): mTORC1 signaling controls central and effector Tregs

The mechanistic/mammalian target of rapamycin (mTOR) has emerged as a critical integrator of signals from the immune microenvironment capable of regulating T cell activation, differentiation and function. The precise role of mTOR in the control of regulatory T cell (Treg) differentiation and functio...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: Sun, Im-Hong, Oh, Min-Hee, Zhao, Liang, Chirag, Patel, H., Arwood, Matthew L., Xu, Wei, Tam, Ada J., Blosser, Richard L., Wen, Jiayu, Powell, Jonathan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089237/
https://ncbi.nlm.nih.gov/pubmed/29884702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701477
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