Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function

The metabolic checkpoint kinase mechanistic/mammalian target of rapamycin (mTOR) regulates natural killer (NK) cell development and function, but the exact underlying mechanisms remain unclear. Here, we show, via conditional deletion of Raptor (mTORC1) or Rictor (mTORC2), that mTORC1 and mTORC2 prom...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Wang, Fangjie, Meng, Meng, Mo, Banghui, Yang, Yao, Ji, Yan, Huang, Pei, Lai, Wenjing, Pan, Xiaodong, You, Tingting, Luo, Hongqin, Guan, Xiao, Deng, Yafei, Yuan, Shunzong, Chu, Jianhong, Namaka, Michael, Hughes, Tiffany, Ye, Lilin, Yu, Jianhua, Li, Xiaohui, Deng, Youcai
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242843/
https://ncbi.nlm.nih.gov/pubmed/30451838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07277-9
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares