HIF-1α versus HIF-2α in endothelial cells and vascular functions: Is there a master in angiogenesis regulation?

Por Skuli, Nicolas, Simon, M. Celeste
Publicado em 2009

Hypoxia-Induced Angiogenesis: Good and Evil

Por Krock, Bryan L., Skuli, Nicolas, Simon, M. Celeste
Publicado em 2011

Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1α

Por Qing, Guoliang, Skuli, Nicolas, Mayes, Patrick A., Pawel, Bruce, Martinez, Daniel, Maris, John M., Simon, M. Celeste
Publicado em 2010

Restricted expression of miR-30c-2-3p and miR-30a-3p in Clear Cell Renal Carcinomas enhances HIF2α activity

Por Mathew, Lijoy K, Lee, Samuel S, Skuli, Nicolas, Rao, Shilpa, Keith, Brian, Nathanson, Katherine L., Lal, Priti, Simon, M, Celeste
Publicado em 2013

A novel cytoprotective function for the DNA repair protein Ku in regulating p53 mRNA translation and function

Por Lamaa, Assala, Le Bras, Morgane, Skuli, Nicolas, Britton, Sébastien, Frit, Philippe, Calsou, Patrick, Prats, Hervé, Cammas, Anne, Millevoi, Stefania
Publicado no EMBO Rep (2016)

Endothelial deletion of hypoxia-inducible factor–2α (HIF-2α) alters vascular function and tumor angiogenesis

Por Skuli, Nicolas, Liu, Liping, Runge, Anja, Wang, Tao, Yuan, Lijun, Patel, Sunny, Iruela-Arispe, Luisa, Simon, M. Celeste, Keith, Brian
Publicado em 2009

Hemodynamic and metabolic diffuse optical monitoring in a mouse model of hindlimb ischemia

Por Mesquita, Rickson C., Skuli, Nicolas, Kim, Meeri N., Liang, Jiaming, Schenkel, Steve, Majmundar, Amar J., Simon, M. Celeste, Yodh, Arjun G.
Publicado em 2010

O(2) Regulates Skeletal Muscle Progenitor Differentiation through Phosphatidylinositol 3-Kinase/AKT Signaling

Por Majmundar, Amar J., Skuli, Nicolas, Mesquita, Rickson C., Kim, Meeri N., Yodh, Arjun G., Nguyen-McCarty, Michelle, Simon, M. Celeste
Publicado em 2012

Multivariate signaling regulation by SHP2 differentially controls proliferation and therapeutic response in glioma cells

Por Furcht, Christopher M., Buonato, Janine M., Skuli, Nicolas, Mathew, Lijoy K., Muñoz Rojas, Andrés R., Simon, M. Celeste, Lazzara, Matthew J.
Publicado em 2014

The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability

Por Krock, Bryan L., Eisinger-Mathason, Tzipora S., Giannoukos, Dionysios N., Shay, Jessica E., Gohil, Mercy, Lee, David S., Nakazawa, Michael S., Sesen, Julie, Skuli, Nicolas, Simon, M. Celeste
Publicado no Blood (2015)

Int6/eIF3e Is Essential for Proliferation and Survival of Human Glioblastoma Cells

Por Sesen, Julie, Cammas, Anne, Scotland, Sarah J., Elefterion, Bertand, Lemarié, Anthony, Millevoi, Stefania, Mathew, Lijoy K., Seva, Cathy, Toulas, Christine, Moyal, Elizabeth Cohen-Jonathan, Skuli, Nicolas
Publicado em 2014

HIF modulation of Wnt signaling regulates skeletal myogenesis in vivo

Por Majmundar, Amar J., Lee, David S. M., Skuli, Nicolas, Mesquita, Rickson C., Kim, Meeri N., Yodh, Arjun G., Nguyen-McCarty, Michelle, Li, Bo, Simon, M. Celeste
Publicado no Development (2015)

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis

Por Eisinger-Mathason, T. S. Karin, Mucaj, Vera, Biju, Kevin M., Nakazawa, Michael S., Gohil, Mercy, Cash, Timothy P., Yoon, Sam S., Skuli, Nicolas, Park, Kyung Min, Gerecht, Sharon, Simon, M. Celeste
Publicado no Proc Natl Acad Sci U S A (2015)

Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer

Por Shay, Jessica E.S., Imtiyaz, Hongxia Z., Sivanand, Sharanya, Durham, Amy C., Skuli, Nicolas, Hsu, Sarah, Mucaj, Vera, Eisinger-Mathason, T.S.Karin, Krock, Bryan L., Giannoukos, Dionysios N., Simon, M.Celeste
Publicado em 2014

Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response

Por Sesen, Julie, Dahan, Perrine, Scotland, Sarah J., Saland, Estelle, Dang, Van-Thi, Lemarié, Anthony, Tyler, Betty M., Brem, Henry, Toulas, Christine, Cohen-Jonathan Moyal, Elizabeth, Sarry, Jean-Emmanuel, Skuli, Nicolas
Publicado no PLoS One (2015)

ATPS-89 LOCAL DELIVERY OF A SMALL-MOLECULE INHIBITOR OF HYPOXIA INDUCIBLE FACTOR-1: A NEW CANDIDATE DRUG FOR BRAIN TUMOR THERAPY

Por Mangraviti, Antonella, Raghavan, Tula, Volpin, Francesco, Skuli, Nicolas, Zhou, Jinyuan, Eberhart, Charles, Rodriguez, Fausto, Sankey, Eric, Gullotti, David, Liu, Ann, Wang, Yuan, Schriefer, Destiny, Brem, Henry, Olivi, Alessandro, Tyler, Betty
Publicado no Neuro Oncol (2015)

ATF4 Regulates MYC-mediated Neuroblastoma Cell Death upon Glutamine Deprivation

Por Qing, Guoliang, Li, Bo, Vu, Annette, Skuli, Nicolas, Walton, Zandra E., Liu, Xueyuan, Mayes, Patrick A., Wise, David R., Thompson, Craig B., Maris, John M., Hogarty, Michael D., Simon, M. Celeste
Publicado em 2012

Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis

Por Eisinger-Mathason, T.S. Karin, Zhang, Minsi, Qiu, Qiong, Skuli, Nicolas, Nakazawa, Michael S., Karakasheva, Tatiana, Mucaj, Vera, Shay, Jessica E.S., Stangenberg, Lars, Sadri, Navid, Puré, Ellen, Yoon, Sam S., Kirsch, David G., Simon, M. Celeste
Publicado em 2013

Feedback circuitry between miR-218 repression and RTK activation in Glioblastoma

Por Mathew, Lijoy K, Huangyang, Peiwei, Mucaj, Vera, Lee, Samuel S., Skuli, Nicolas, Eisinger-Mathason, T.S. Karin, Biju, Kevin, Li, Bo, Venneti, Sriram, Lal, Priti, Lathia, Justin D, Rich, Jeremy N, Keith, Brian, Simon, M Celeste
Publicado no Sci Signal (2015)

Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes

Por Skuli, Nicolas, Majmundar, Amar J., Krock, Bryan L., Mesquita, Rickson C., Mathew, Lijoy K., Quinn, Zachary L., Runge, Anja, Liu, Liping, Kim, Meeri N., Liang, Jiaming, Schenkel, Steven, Yodh, Arjun G., Keith, Brian, Simon, M. Celeste
Publicado em 2012