Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes

Localized tissue hypoxia is a consequence of vascular compromise or rapid cellular proliferation and is a potent inducer of compensatory angiogenesis. The oxygen-responsive transcriptional regulator hypoxia-inducible factor 2α (HIF-2α) is highly expressed in vascular ECs and, along with HIF-1α, acti...

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Autori principali: Skuli, Nicolas, Majmundar, Amar J., Krock, Bryan L., Mesquita, Rickson C., Mathew, Lijoy K., Quinn, Zachary L., Runge, Anja, Liu, Liping, Kim, Meeri N., Liang, Jiaming, Schenkel, Steven, Yodh, Arjun G., Keith, Brian, Simon, M. Celeste
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314446/
https://ncbi.nlm.nih.gov/pubmed/22426208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57322
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