Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes

Localized tissue hypoxia is a consequence of vascular compromise or rapid cellular proliferation and is a potent inducer of compensatory angiogenesis. The oxygen-responsive transcriptional regulator hypoxia-inducible factor 2α (HIF-2α) is highly expressed in vascular ECs and, along with HIF-1α, acti...

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Bibliografski detalji
Glavni autori: Skuli, Nicolas, Majmundar, Amar J., Krock, Bryan L., Mesquita, Rickson C., Mathew, Lijoy K., Quinn, Zachary L., Runge, Anja, Liu, Liping, Kim, Meeri N., Liang, Jiaming, Schenkel, Steven, Yodh, Arjun G., Keith, Brian, Simon, M. Celeste
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314446/
https://ncbi.nlm.nih.gov/pubmed/22426208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57322
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