Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27

Por Villarino, Alejandro V, Hunter, Christopher A
Publicado em 2004

IL-13-producing Th1 and Th17 cells characterize adaptive responses to both self and foreign antigens

Por Gallo, Eugenio, Katzman, Shoshana, Villarino, Alejandro V.
Publicado em 2012

STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and independent mechanisms

Por Villarino, Alejandro V., Gallo, Eugenio, Abbas, Abul K.
Publicado em 2010

Mechanisms of Jak/STAT signaling in immunity and disease

Por Villarino, Alejandro V., Kanno, Yuka, O’Shea, John J.
Publicado no J Immunol (2015)

IL-27 shakes up the establishment of ectopic lymphoid structures

Por Villarino, Alejandro V., O’Shea, John J., Hunter, Christopher A.
Publicado no J Exp Med (2015)

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

Por Lohr, Jens, Knoechel, Birgit, Wang, Jing Jing, Villarino, Alejandro V., Abbas, Abul K.
Publicado em 2006

Cutting Edge: The Th1 Response Inhibits the Generation of Peripheral Regulatory T Cells

Por Caretto, David, Katzman, Shoshana D., Villarino, Alejandro V., Gallo, Eugenio, Abbas, Abul K.
Publicado em 2009

Posttranscriptional Silencing of Effector Cytokine mRNA Underlies the Anergic Phenotype of Self-Reactive T Cells

Por Villarino, Alejandro V., Katzman, Shoshana D., Gallo, Eugenio, Miller, Omer, Jiang, Shuwei, McManus, Michael T., Abbas, Abul K.
Publicado em 2011

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals

Por Villarino, Alejandro V., Tato, Cristina M., Stumhofer, Jason S., Yao, Zhengju, Cui, Yongzhi K., Hennighausen, Lothar, O'Shea, John J., Hunter, Christopher A.
Publicado em 2007

Induction of Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Restricts Clonal Expansion of Helper T Cells

Por Doyle, Alden M., Mullen, Alan C., Villarino, Alejandro V., Hutchins, Anne S., High, Frances A., Lee, Hubert W., Thompson, Craig B., Reiner, Steven L.
Publicado em 2001

Duration of antigen receptor signaling determines T-cell tolerance or activation

Por Katzman, Shoshana D., O'Gorman, William E., Villarino, Alejandro V., Gallo, Eugenio, Friedman, Rachel S., Krummel, Matthew F., Nolan, Garry P., Abbas, Abul K.
Publicado em 2010

An autoregulatory enhancer controls mammary-specific STAT5 functions

Por Metser, Gil, Shin, Ha Youn, Wang, Chaochen, Yoo, Kyung Hyun, Oh, Sumin, Villarino, Alejandro V., O'Shea, John J., Kang, Keunsoo, Hennighausen, Lothar
Publicado no Nucleic Acids Res (2016)

Transcriptional and epigenetic networks that drive helper T cell identities

Por Shih, Han-Yu, Sciumè, Giuseppe, Poholek, Amanda C, Vahedi, Golnaz, Hirahara, Kiyoshi, Villarino, Alejandro V, Bonelli, Michael, Bosselut, Remy, Kanno, Yuka, Muljo, Stefan A, O’Shea, John J.
Publicado no Immunol Rev (2014)

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions

Por Villarino, Alejandro, Laurence, Arian, Robinson, Gertraud W, Bonelli, Michael, Dema, Barbara, Afzali, Behdad, Shih, Han-Yu, Sun, Hong-Wei, Brooks, Stephen R, Hennighausen, Lothar, Kanno, Yuka, O'Shea, John J
Publicado no eLife (2016)

T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire

Por Bronevetsky, Yelena, Villarino, Alejandro V., Eisley, Christopher J., Barbeau, Rebecca, Barczak, Andrea J., Heinz, Gitta A., Kremmer, Elisabeth, Heissmeyer, Vigo, McManus, Michael T., Erle, David J., Rao, Anjana, Ansel, K. Mark
Publicado em 2013

Distinct requirements for T-bet in gut innate lymphoid cells

Por Sciumé, Giuseppe, Hirahara, Kiyoshi, Takahashi, Hayato, Laurence, Arian, Villarino, Alejandro V., Singleton, Kentner L., Spencer, Sean P., Wilhelm, Christoph, Poholek, Amanda C., Vahedi, Golnaz, Kanno, Yuka, Belkaid, Yasmine, O'Shea, John J.
Publicado em 2012

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Por Chang, Chih-Hao, Curtis, Jonathan D., Maggi, Leonard B., Faubert, Brandon, Villarino, Alejandro V., O’Sullivan, David, Huang, Stanley Ching-Cheng, van der Windt, Gerritje J.W., Blagih, Julianna, Qiu, Jing, Weber, Jason D., Pearce, Edward J., Jones, Russell G., Pearce, Erika L.
Publicado em 2013

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3

Por Steward-Tharp, Scott M., Laurence, Arian, Kanno, Yuka, Kotlyar, Alex, Villarino, Alejandro V., Sciume, Giuseppe, Kuchen, Stefan, Resch, Wolfgang, Wohlfert, Elizabeth A., Jiang, Kan, Hirahara, Kiyoshi, Vahedi, Golnaz, Sun, Hong-wei, Feigenbaum, Lionel, Milner, Joshua D., Holland, Steven M., Casellas, Rafael, Powrie, Fiona, O'Shea, John J.
Publicado em 2014

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

Por Canna, Scott W., de Jesus, Adriana Almeida, Gouni, Sushanth, Brooks, Stephen R., Marrero, Bernadette, Liu, Yin, DiMattia, Michael A., Zaal, Kristien J.M., Montealegre Sanchez, Gina A., Kim, Hanna, Chapelle, Dawn, Plass, Nicole, Huang, Yan, Villarino, Alejandro V., Biancotto, Angelique, Fleisher, Thomas A., Duncan, Joseph A., O’Shea, John J, Benseler, Susanne, Grom, Alexei, Deng, Zuoming, Laxer, Ronald M, Goldbach-Mansky, Raphaela
Publicado em 2014