Distinct requirements for T-bet in gut innate lymphoid cells

Interleukin (IL)-22–producing innate lymphoid cells (ILCs; ILC22) comprise a heterogeneous population of cells that are dependent on the transcription factor retinoid-related orphan γt (RORγt) and are critical for barrier function of the intestinal mucosa. A distinct ILC22 subset expresses the natur...

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Bibliographische Detailangaben
Hauptverfasser: Sciumé, Giuseppe, Hirahara, Kiyoshi, Takahashi, Hayato, Laurence, Arian, Villarino, Alejandro V., Singleton, Kentner L., Spencer, Sean P., Wilhelm, Christoph, Poholek, Amanda C., Vahedi, Golnaz, Kanno, Yuka, Belkaid, Yasmine, O'Shea, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526352/
https://ncbi.nlm.nih.gov/pubmed/23209316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122097
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