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Mechanisms Underlying Helper T cell Plasticity: Implications for Immune-mediated Disease

CD4 helper T cells are critical for proper immune cell homeostasis and host defense, but are also major contributes to immune and inflammatory disease. Arising from a simple, biphasic model of differentiation, Th1 and Th2 cells, a bewildering number of fates seem to possible for helper T cells. To w...

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Bibliographic Details
Main Authors: Hirahara, Kiyoshi, Poholek, Amanda, Vahedi, Golnaz, Laurence, Arian, Kanno, Yuka, Milner, Joshua D., O’Shea, John J.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677748/
https://ncbi.nlm.nih.gov/pubmed/23622118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.03.015
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