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Transcriptional and Epigenetic Control of T Cell Lineage Specification: Molecular Mechanisms Underlying Commitment and Plasticity

Helper T cell differentiation occurs in the context of the extracelluar cytokine milieu evoked by diverse microbes and other pathogenic stimuli along with T cell receptor stimulation. The culmination of these signals results in specification of T helper lineages, which occurs through the combinatori...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kanno, Yuka, Vahedi, Golnaz, Hirahara, Kiyoshi, Singleton, Kentner, O’Shea, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314163/
https://ncbi.nlm.nih.gov/pubmed/22224760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-020711-075058
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