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Mechanisms of Jak/STAT signaling in immunity and disease

More than 2 decades ago, experiments on the antiviral mechanisms of interferons led to the discovery of Janus kinases (JAK) and their downstream effectors, the signal transducer of activation (STAT) proteins. This pathway has since become a paradigm for membrane to nucleus signaling and has come to...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Villarino, Alejandro V., Kanno, Yuka, O’Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524500/
https://ncbi.nlm.nih.gov/pubmed/25527793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401867
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