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The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention
The Janus kinase (JAK), signal transducer of activation (STAT) pathway, discovered by investigating interferon gene induction, is now recognized as an evolutionarily conserved signaling pathway employed by diverse cytokines, interferons, growth factors, and related molecules. This pathway provides a...
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| Publicado no: | Annu Rev Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5634336/ https://ncbi.nlm.nih.gov/pubmed/25587654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-051113-024537 |
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