Induction of Cytotoxic T Lymphocyte Antigen 4 (Ctla-4) Restricts Clonal Expansion of Helper T Cells

Cytotoxic T lymphocyte antigen (CTLA)-4 plays an essential role in immunologic homeostasis. How this negative regulator of T cell activation executes its functions has remained controversial. We now provide evidence that CTLA-4 mediates a cell-intrinsic counterbalance to restrict the clonal expansio...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Doyle, Alden M., Mullen, Alan C., Villarino, Alejandro V., Hutchins, Anne S., High, Frances A., Lee, Hubert W., Thompson, Craig B., Reiner, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193479/
https://ncbi.nlm.nih.gov/pubmed/11581312
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados