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IL-13-producing Th1 and Th17 cells characterize adaptive responses to both self and foreign antigens
In helper T cells, IL-13 is traditionally considered a Th2-type cytokine that is co-expressed with IL-4. Using mouse models of immunization and autoimmunity, we demonstrate that IL-13 is frequently uncoupled from IL-4, and that it can be produced by both IFN-γ(+) Th1 cells and IL-17(+) Th17 cells. W...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3811006/ https://ncbi.nlm.nih.gov/pubmed/22684943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142227 |
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