Decidual Interleukin-22-Producing CD4+ T Cells (Th17/Th0/IL-22+ and Th17/Th2/IL-22+, Th2/IL-22+, Th0/IL-22+), Which Also Produce IL-4, Are Involved in the Success of Pregnancy

Trophoblast expressing paternal HLA-C resembles a semiallograft, and could be rejected by maternal T cells. IL-22 seems to be involved in allograft rejection and thus could be responsible for miscarriages. We examined the role of decidual IL-22-producing CD4+ T on human pregnancy. In those experienc...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Logiodice, Federica, Lombardelli, Letizia, Kullolli, Ornela, Haller, Herman, Maggi, Enrico, Rukavina, Daniel, Piccinni, Marie-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359245/
https://ncbi.nlm.nih.gov/pubmed/30669479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020428
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