Medroxyprogesterone Acetate Decreases Th1, Th17, and Increases Th22 Responses via AHR Signaling Which Could Affect Susceptibility to Infections and Inflammatory Disease

A synthetic progestin, medroxyprogesterone acetate (MPA), was used in a novel study to determine progestin effects on human purified macrophages and Th1, Th2, Th17, Th22 cells. MPA concentrations were equivalent to those in the serum of women after 6 and 9 months of progestin use. MPA has no effect...

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Publicat a:Front Immunol
Autors principals: Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Kullolli, Ornela, Maggi, Enrico, Barkley, Marylynn S.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456711/
https://ncbi.nlm.nih.gov/pubmed/31001262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00642
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