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IL-13 Regulates Th17 Secretion of IL-17A in an IL-10-Dependent Manner

IL-13 is a central mediator of airway hyperreactivity and mucus expression, both hallmarks of asthma. IL-13 is found in the sputum of patients with asthma; therefore, IL-13 is an attractive drug target for treating asthma. We have previously shown that IL-13 inhibits Th17 cell production of IL-17A a...

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Detalhes bibliográficos
Main Authors: Newcomb, Dawn C., Boswell, Madison G., Huckabee, Matthew M., Goleniewska, Kasia, Dulek, Daniel E., Reiss, Sara, Lukacs, Nicholas W., Kolls, Jay K., Peebles, R. Stokes
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262924/
https://ncbi.nlm.nih.gov/pubmed/22210911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102216
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