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Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
A “switch” from oxidative phosphorylation (OXPHOS) to aerobic glycolysis is a hallmark of T cell activation and is thought to be required to meet the metabolic demands of proliferation. However, why proliferating cells adopt this less efficient metabolism, especially in an oxygen-replete environment...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804311/ https://ncbi.nlm.nih.gov/pubmed/23746840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.016 |
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