Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells

TLR agonists initiate a rapid activation program in dendritic cells (DCs) that requires support from metabolic and bioenergetic resources. We found previously that TLR signaling promotes aerobic glycolysis and a decline in oxidative phosphorylation (OXHPOS) and that glucose restriction prevents acti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Everts, Bart, Amiel, Eyal, van der Windt, Gerritje J. W., Freitas, Tori C., Chott, Robert, Yarasheski, Kevin E., Pearce, Erika L., Pearce, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423780/
https://ncbi.nlm.nih.gov/pubmed/22786879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-419747
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados