One-step Purification of Twin-Strep-tagged Proteins and Their Complexes on Strep-Tactin Resin Cross-linked With Bis(sulfosuccinimidyl) Suberate (BS3)

Por Ivanov, Konstantin I, Bašić, Marta, Varjosalo, Markku, Mäkinen, Kristiina
Publicado em 2014

Recognition of Malondialdehyde-modified Proteins by the C Terminus of Complement Factor H Is Mediated via the Polyanion Binding Site and Impaired by Mutations Found in Atypical Hem...

Por Hyvärinen, Satu, Uchida, Koji, Varjosalo, Markku, Jokela, Reija, Jokiranta, T. Sakari
Publicado em 2014

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion

Por Sugiyama, Nami, Gucciardo, Erika, Tatti, Olga, Varjosalo, Markku, Hyytiäinen, Marko, Gstaiger, Matthias, Lehti, Kaisa
Publicado em 2013

Predegenerated Schwann cells–a novel prospect for cell therapy for glaucoma: neuroprotection, neuroregeneration and neuroplasticity

Por Smedowski, Adrian, Liu, Xiaonan, Pietrucha-Dutczak, Marita, Matuszek, Iwona, Varjosalo, Markku, Lewin-Kowalik, Joanna
Publicado no Sci Rep (2016)

Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1

Por Hauri, Simon, Wepf, Alexander, van Drogen, Audrey, Varjosalo, Markku, Tapon, Nic, Aebersold, Ruedi, Gstaiger, Matthias
Publicado em 2013

Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung

Por Ittner, Arne, Block, Helena, Reichel, Christoph A., Varjosalo, Markku, Gehart, Helmuth, Sumara, Grzegorz, Gstaiger, Matthias, Krombach, Fritz, Zarbock, Alexander, Ricci, Romeo
Publicado em 2012

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase–FGFR4 complex

Por Sugiyama, Nami, Varjosalo, Markku, Meller, Pipsa, Lohi, Jouko, Chan, Kui Ming, Zhou, Zhongjun, Alitalo, Kari, Taipale, Jussi, Keski-Oja, Jorma, Lehti, Kaisa
Publicado em 2010

Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage

Por Pfisterer, Simon G., Gateva, Gergana, Horvath, Peter, Pirhonen, Juho, Salo, Veijo T., Karhinen, Leena, Varjosalo, Markku, Ryhänen, Samppa J., Lappalainen, Pekka, Ikonen, Elina
Publicado no Nat Commun (2017)

KSHV Reactivation from Latency Requires Pim-1 and Pim-3 Kinases to Inactivate the Latency-Associated Nuclear Antigen LANA

Por Cheng, Fang, Weidner-Glunde, Magdalena, Varjosalo, Markku, Rainio, Eeva-Marja, Lehtonen, Anne, Schulz, Thomas F., Koskinen, Päivi J., Taipale, Jussi, Ojala, Päivi M.
Publicado em 2009

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles

Por Haapasalo, Karita, van Kessel, Kok, Nissilä, Eija, Metso, Jari, Johansson, Tiira, Miettinen, Sini, Varjosalo, Markku, Kirveskari, Juha, Kuusela, Pentti, Chroni, Angelika, Jauhiainen, Matti, van Strijp, Jos, Jokiranta, T. Sakari
Publicado no J Biol Chem (2015)

Functional and Structural Properties of a Novel Protein and Virulence Factor (Protein sHIP) in Streptococcus pyogenes

Por Wisniewska, Magdalena, Happonen, Lotta, Kahn, Fredrik, Varjosalo, Markku, Malmström, Lars, Rosenberger, George, Karlsson, Christofer, Cazzamali, Giuseppe, Pozdnyakova, Irina, Frick, Inga-Maria, Björck, Lars, Streicher, Werner, Malmström, Johan, Wikström, Mats
Publicado em 2014

HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix

Por Paveliev, Mikhail, Fenrich, Keith K., Kislin, Mikhail, Kuja-Panula, Juha, Kulesskiy, Evgeny, Varjosalo, Markku, Kajander, Tommi, Mugantseva, Ekaterina, Ahonen-Bishopp, Anni, Khiroug, Leonard, Kulesskaya, Natalia, Rougon, Geneviève, Rauvala, Heikki
Publicado no Sci Rep (2016)

Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells

Por Santio, Niina M., Landor, Sebastian K.-J., Vahtera, Laura, Ylä-Pelto, Jani, Paloniemi, Elina, Imanishi, Susumu Y., Corthals, Garry, Varjosalo, Markku, Manoharan, Ganesh Babu, Uri, Asko, Lendahl, Urban, Sahlgren, Cecilia, Koskinen, Päivi J.
Publicado no Oncotarget (2016)

Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication

Por Balistreri, Giuseppe, Viiliäinen, Johanna, Turunen, Mikko, Diaz, Raquel, Lyly, Lauri, Pekkonen, Pirita, Rantala, Juha, Ojala, Krista, Sarek, Grzegorz, Teesalu, Mari, Denisova, Oxana, Peltonen, Karita, Julkunen, Ilkka, Varjosalo, Markku, Kainov, Denis, Kallioniemi, Olli, Laiho, Marikki, Taipale, Jussi, Hautaniemi, Sampsa, Ojala, Päivi M.
Publicado no PLoS Pathog (2016)

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo

Por Wei, Gong-Hong, Badis, Gwenael, Berger, Michael F, Kivioja, Teemu, Palin, Kimmo, Enge, Martin, Bonke, Martin, Jolma, Arttu, Varjosalo, Markku, Gehrke, Andrew R, Yan, Jian, Talukder, Shaheynoor, Turunen, Mikko, Taipale, Mikko, Stunnenberg, Hendrik G, Ukkonen, Esko, Hughes, Timothy R, Bulyk, Martha L, Taipale, Jussi
Publicado em 2010

Uterine leiomyoma-linked MED12 mutations disrupt Mediator-associated CDK activity

Por Turunen, Mikko, Spaeth, Jason M., Keskitalo, Salla, Park, Min Ju, Kivioja, Teemu, Clark, Alison D., Mäkinen, Netta, Gao, Fangjian, Palin, Kimmo, Nurkkala, Helka, Vähärautio, Anna, Aavikko, Mervi, Kämpjärvi, Kati, Vahteristo, Pia, Kim, Chongwoo A., Aaltonen, Lauri A., Varjosalo, Markku, Taipale, Jussi, Boyer, Thomas G.
Publicado em 2014