Role for formin-like 1-dependent acto-myosin assembly in lipid droplet dynamics and lipid storage

Lipid droplets (LDs) are cellular organelles specialized in triacylglycerol (TG) storage undergoing homotypic clustering and fusion. In non-adipocytic cells with numerous LDs this is balanced by poorly understood droplet dissociation mechanisms. We identify non-muscle myosin IIa (NMIIa/MYH-9) and fo...

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Publicado no:Nat Commun
Main Authors: Pfisterer, Simon G., Gateva, Gergana, Horvath, Peter, Pirhonen, Juho, Salo, Veijo T., Karhinen, Leena, Varjosalo, Markku, Ryhänen, Samppa J., Lappalainen, Pekka, Ikonen, Elina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380971/
https://ncbi.nlm.nih.gov/pubmed/28361956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14858
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