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Seipin regulates ER–lipid droplet contacts and cargo delivery
Seipin is an endoplasmic reticulum (ER) membrane protein implicated in lipid droplet (LD) biogenesis and mutated in severe congenital lipodystrophy (BSCL2). Here, we show that seipin is stably associated with nascent ER–LD contacts in human cells, typically via one mobile focal point per LD. Seipin...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5167346/ https://ncbi.nlm.nih.gov/pubmed/27879284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695170 |
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