Informational limits of biological organisms

por Taipale, Jussi
Publicado en EMBO J (2018)

MODER2: first-order Markov modeling and discovery of monomeric and dimeric binding motifs

por Toivonen, Jarkko, Das, Pratyush K, Taipale, Jussi, Ukkonen, Esko
Publicado en Bioinformatics (2020)

Reply to “CRISPR screens are feasible in TP53 wild‐type cells”

por Haapaniemi, Emma, Botla, Sandeep, Persson, Jenna, Schmierer, Bernhard, Taipale, Jussi
Publicado en Mol Syst Biol (2019)

Hepatocyte Growth Factor Releases Mink Epithelial Cells from Transforming Growth Factor β1-Induced Growth Arrest by Restoring Cdk6 Expression and Cyclin E-Associated Cdk2 Activit...

por Tsubari, Minna, Taipale, Jussi, Tiihonen, Erja, Keski-Oja, Jorma, Laiho, Marikki
Publicado 1999

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

por Chen, James K., Taipale, Jussi, Cooper, Michael K., Beachy, Philip A.
Publicado 2002

Modular discovery of monomeric and dimeric transcription factor binding motifs for large data sets

por Toivonen, Jarkko, Kivioja, Teemu, Jolma, Arttu, Yin, Yimeng, Taipale, Jussi, Ukkonen, Esko
Publicado en Nucleic Acids Res (2018)

Small molecule modulation of Smoothened activity

por Chen, James K., Taipale, Jussi, Young, Keith E., Maiti, Tapan, Beachy, Philip A.
Publicado 2002

CRISPR/Cas9 screening using unique molecular identifiers

por Schmierer, Bernhard, Botla, Sandeep K, Zhang, Jilin, Turunen, Mikko, Kivioja, Teemu, Taipale, Jussi
Publicado en Mol Syst Biol (2017)

Transcription factor family‐specific DNA shape readout revealed by quantitative specificity models

por Yang, Lin, Orenstein, Yaron, Jolma, Arttu, Yin, Yimeng, Taipale, Jussi, Shamir, Ron, Rohs, Remo
Publicado en Mol Syst Biol (2017)

Transcriptional Networks Controlling the Cell Cycle

por Bonke, Martin, Turunen, Mikko, Sokolova, Maria, Vähärautio, Anna, Kivioja, Teemu, Taipale, Minna, Björklund, Mikael, Taipale, Jussi
Publicado 2013

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12

por Mäkinen, Netta, Aavikko, Mervi, Heikkinen, Tuomas, Taipale, Minna, Taipale, Jussi, Koivisto-Korander, Riitta, Bützow, Ralf, Vahteristo, Pia
Publicado en PLoS Genet (2016)

Transcriptionally active enhancers in human cancer cells

por Lidschreiber, Katja, Jung, Lisa A, von der Emde, Henrik, Dave, Kashyap, Taipale, Jussi, Cramer, Patrick, Lidschreiber, Michael
Publicado en Mol Syst Biol (2021)

Structural insights into the DNA-binding specificity of E2F family transcription factors

por Morgunova, Ekaterina, Yin, Yimeng, Jolma, Arttu, Dave, Kashyap, Schmierer, Bernhard, Popov, Alexander, Eremina, Nadejda, Nilsson, Lennart, Taipale, Jussi
Publicado en Nat Commun (2015)

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer

por Pitkänen, Esa, Cajuso, Tatiana, Katainen, Riku, Kaasinen, Eevi, Välimäki, Niko, Palin, Kimmo, Taipale, Jussi, Aaltonen, Lauri A., Kilpivaara, Outi
Publicado 2014

Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima

por Morgunova, Ekaterina, Yin, Yimeng, Das, Pratyush K, Jolma, Arttu, Zhu, Fangjie, Popov, Alexander, Xu, You, Nilsson, Lennart, Taipale, Jussi
Publicado en eLife (2018)

Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion

por Sokolova, Maria, Turunen, Mikko, Mortusewicz, Oliver, Kivioja, Teemu, Herr, Patrick, Vähärautio, Anna, Björklund, Mikael, Taipale, Minna, Helleday, Thomas, Taipale, Jussi
Publicado en Cell Cycle (2016)

VEGFR-3 and Its Ligand VEGF-C Are Associated with Angiogenesis in Breast Cancer

por Valtola, Reija, Salven, Petri, Heikkilä, Päivi, Taipale, Jussi, Joensuu, Heikki, Rehn, Marko, Pihlajaniemi, Taina, Weich, Herbert, deWaal, Robert, Alitalo, Kari
Publicado 1999

Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos

por Haiko, Paula, Makinen, Taija, Keskitalo, Salla, Taipale, Jussi, Karkkainen, Marika J., Baldwin, Megan E., Stacker, Steven A., Achen, Marc G., Alitalo, Kari
Publicado 2008

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase–FGFR4 complex

por Sugiyama, Nami, Varjosalo, Markku, Meller, Pipsa, Lohi, Jouko, Chan, Kui Ming, Zhou, Zhongjun, Alitalo, Kari, Taipale, Jussi, Keski-Oja, Jorma, Lehti, Kaisa
Publicado 2010

KSHV Reactivation from Latency Requires Pim-1 and Pim-3 Kinases to Inactivate the Latency-Associated Nuclear Antigen LANA

por Cheng, Fang, Weidner-Glunde, Magdalena, Varjosalo, Markku, Rainio, Eeva-Marja, Lehtonen, Anne, Schulz, Thomas F., Koskinen, Päivi J., Taipale, Jussi, Ojala, Päivi M.
Publicado 2009