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Modular discovery of monomeric and dimeric transcription factor binding motifs for large data sets

In some dimeric cases of transcription factor (TF) binding, the specificity of dimeric motifs has been observed to differ notably from what would be expected were the two factors to bind to DNA independently of each other. Current motif discovery methods are unable to learn monomeric and dimeric mot...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Toivonen, Jarkko, Kivioja, Teemu, Jolma, Arttu, Yin, Yimeng, Taipale, Jussi, Ukkonen, Esko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934673/
https://ncbi.nlm.nih.gov/pubmed/29385521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky027
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