Conservation of transcription factor binding specificities across 600 million years of bilateria evolution

Divergent morphology of species has largely been ascribed to genetic differences in the tissue-specific expression of proteins, which could be achieved by divergence in cis-regulatory elements or by altering the binding specificity of transcription factors (TFs). The relative importance of the latte...

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Veröffentlicht in:eLife
Hauptverfasser: Nitta, Kazuhiro R, Jolma, Arttu, Yin, Yimeng, Morgunova, Ekaterina, Kivioja, Teemu, Akhtar, Junaid, Hens, Korneel, Toivonen, Jarkko, Deplancke, Bart, Furlong, Eileen E M, Taipale, Jussi
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2015
Schlagworte:
Genes and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362205/
https://ncbi.nlm.nih.gov/pubmed/25779349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04837
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