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Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion
To identify cell cycle regulators that enable cancer cells to replicate DNA and divide in an unrestricted manner, we performed a parallel genome-wide RNAi screen in normal and cancer cell lines. In addition to many shared regulators, we found that tumor and normal cells are differentially sensitive...
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283814/ https://ncbi.nlm.nih.gov/pubmed/27929715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1261765 |
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