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Nucleosome depleted regions in cell-cycle-regulated promoters ensure reliable gene expression in every cell cycle

Many promoters in eukaryotes have nucleosome depleted regions (NDR) containing transcription factor binding sites (TFBS). However, the functional significance of NDR is not well understood. Here, we examine NDR function in two cell-cycle-regulated promoters, CLN2pr and HOpr, by varying nucleosomal c...

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Bibliografiska uppgifter
Huvudupphovsmän: Bai, Lu, Charvin, Gilles, Siggia, Eric, Cross, Frederick
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867244/
https://ncbi.nlm.nih.gov/pubmed/20412770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.02.007
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