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Nucleosome depleted regions in cell-cycle-regulated promoters ensure reliable gene expression in every cell cycle

Many promoters in eukaryotes have nucleosome depleted regions (NDR) containing transcription factor binding sites (TFBS). However, the functional significance of NDR is not well understood. Here, we examine NDR function in two cell-cycle-regulated promoters, CLN2pr and HOpr, by varying nucleosomal c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bai, Lu, Charvin, Gilles, Siggia, Eric, Cross, Frederick
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867244/
https://ncbi.nlm.nih.gov/pubmed/20412770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.02.007
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