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Positive feedback of G1 cyclins ensures coherent cell cycle entry
In budding yeast, the Start checkpoint integrates multiple internal and external signals into an all-or-none decision to enter the cell cycle. Here, we show that Start behaves like a switch due to systems-level feedback in the regulatory network. In contrast to current models proposing a linear casc...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2606905/ https://ncbi.nlm.nih.gov/pubmed/18633409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07118 |
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