Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles

The alternative pathway of complement is an important part of the innate immunity response against foreign particles invading the human body. To avoid damage to host cells, it needs to be efficiently down-regulated by plasma factor H (FH) as exemplified by various diseases caused by mutations in its...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Haapasalo, Karita, van Kessel, Kok, Nissilä, Eija, Metso, Jari, Johansson, Tiira, Miettinen, Sini, Varjosalo, Markku, Kirveskari, Juha, Kuusela, Pentti, Chroni, Angelika, Jauhiainen, Matti, van Strijp, Jos, Jokiranta, T. Sakari
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661410/
https://ncbi.nlm.nih.gov/pubmed/26468283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669226
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