Structure-switching biosensors: inspired by Nature

Por Vallée-Bélisle, Alexis, Plaxco, Kevin W.
Publicado em 2010

Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors

Por Vallée-Bélisle, Alexis, Ricci, Francesco, Plaxco, Kevin W.
Publicado em 2009

High-Precision, In Vitro Validation of the Sequestration Mechanism for Generating Ultrasensitive Dose-Response Curves in Regulatory Networks

Por Ricci, Francesco, Vallée-Bélisle, Alexis, Plaxco, Kevin W.
Publicado em 2011

Engineering biosensors with extended, narrowed, or arbitrarily edited dynamic range

Por Vallée-Bélisle, Alexis, Ricci, Francesco, Plaxco, Kevin W.
Publicado em 2012

General Strategy to Introduce pH-Induced Allostery in DNA-Based Receptors to Achieve Controlled Release of Ligands

Por Porchetta, Alessandro, Idili, Andrea, Vallée-Bélisle, Alexis, Ricci, Francesco
Publicado no Nano Lett (2015)

The rational design of allosteric inhibitors and activators using the population-shift model: in vitro validation and application to an artificial biosensor

Por Ricci, Francesco, Vallée-Bélisle, Alexis, Porchetta, Alessandro, Plaxco, Kevin W.
Publicado em 2012

Allosterically tunable, DNA-based switches triggered by heavy metals

Por Porchetta, Alessandro, Vallée-Bélisle, Alexis, Plaxco, Kevin W., Ricci, Francesco
Publicado em 2013

Using distal site mutations and allosteric inhibition to tune, extend and narrow the useful dynamic range of aptamer-based sensors

Por Porchetta, Alessandro, Vallée-Bélisle, Alexis, Plaxco, Kevin W., Ricci, Francesco
Publicado em 2012

Thermodynamic Basis For Engineering High Affinity, High Specificity Binding-Induced DNA Clamp Nanoswitches

Por Idili, Andrea, Plaxco, Kevin W., Vallée-Bélisle, Alexis, Ricci, Francesco
Publicado no ACS Nano (2013)

Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors

Por Simon, Anna J., Vallée-Bélisle, Alexis, Ricci, Francesco, Plaxco, Kevin W.
Publicado em 2014

Enzyme-Operated DNA-Based Nanodevices

Por Del Grosso, Erica, Dallaire, Anne-Marie, Vallée-Bélisle, Alexis, Ricci, Francesco
Publicado no Nano Lett (2015)

Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range

Por Kang, Di, Vallée-Bélisle, Alexis, Porchetta, Alessandro, Plaxco, Kevin W., Ricci, Francesco
Publicado em 2012

Bio-electrochemical switches for the quantitative detection of antibodies directly in whole blood

Por Vallée-Bélisle, Alexis, Ricci, Francesco, Uzawa, Takanori, Xia, Fan, Plaxco, Kevin W.
Publicado em 2012

A modular, DNA-based “beacon” for the single-step fluorescent measurement of antibodies and other proteins()

Por Ranallo, Simona, Rossetti, Marianna, Plaxco, Kevin W., Vallée-Bélisle, Alexis, Ricci, Francesco
Publicado no Angew Chem Int Ed Engl (2015)

Antibody-powered nucleic acid release using a DNA-based nanomachine

Por Ranallo, Simona, Prévost-Tremblay, Carl, Idili, Andrea, Vallée-Bélisle, Alexis, Ricci, Francesco
Publicado no Nat Commun (2017)

Using Nature’s “Tricks” To Rationally Tune the Binding Properties of Biomolecular Receptors

Por Ricci, Francesco, Vallée-Bélisle, Alexis, Simon, Anna J., Porchetta, Alessandro, Plaxco, Kevin W.
Publicado no Acc Chem Res (2016)

Employing the metabolic “branch point effect” to generate an all-or-none, digital-like response in enzymatic outputs and enzyme-based sensors

Por Perez Rafael, Sandra, Vallee-Belisle, Alexis, Fabregas, Esteve, Plaxco, Kevin, Palleschi, Giuseppe, Ricci, Francesco
Publicado em 2011

Transcription Factor Beacons for the Quantitative Detection of DNA Binding Activity

Por Vallée-Bélisle, Alexis, Bonham, Andrew J., Reich, Norbert O., Ricci, Francesco, Plaxco, Kevin W.
Publicado em 2011

Entropic and Electrostatic Effects on the Folding Free Energy of a Surface-Attached Biomolecule: An Experimental and Theoretical Study

Por Watkins, Herschel M., Vallée-Bélisle, Alexis, Ricci, Francesco, Makarov, Dmitrii E., Plaxco, Kevin W.
Publicado em 2012

Using the population-shift mechanism to rationally introduce “Hill-type” cooperativity into a normally non-cooperative receptor

Por Simon, Anna J., Vallée-Bélisle, Alexis, Ricci, Francesco, Watkins, Herschel M., Plaxco, Kevin W.
Publicado no Angew Chem Int Ed Engl (2014)