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Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors

Binding-induced biomolecular switches are used throughout nature and, increasingly, throughout biotechnology for the detection of chemical moieties and the subsequent transduction of this detection into useful outputs. Here we show that the thermodynamics of these switches are quantitatively describ...

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Bibliografiska uppgifter
Huvudupphovsmän: Vallée-Bélisle, Alexis, Ricci, Francesco, Plaxco, Kevin W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728975/
https://ncbi.nlm.nih.gov/pubmed/19666496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904005106
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