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Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors
Binding-induced biomolecular switches are used throughout nature and, increasingly, throughout biotechnology for the detection of chemical moieties and the subsequent transduction of this detection into useful outputs. Here we show that the thermodynamics of these switches are quantitatively describ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728975/ https://ncbi.nlm.nih.gov/pubmed/19666496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904005106 |
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