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Thermodynamic Basis For Engineering High Affinity, High Specificity Binding-Induced DNA Clamp Nanoswitches

Naturally occurring chemoreceptors almost invariably employ structure-switching mechanisms, an observation that has inspired the use of biomolecular switches in a wide range of artificial technologies in the areas of diagnostics, imaging, and synthetic biology. In one mechanism for generating such b...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Idili, Andrea, Plaxco, Kevin W., Vallée-Bélisle, Alexis, Ricci, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281346/
https://ncbi.nlm.nih.gov/pubmed/24219761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn404305e
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