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Thermodynamic Basis For Engineering High Affinity, High Specificity Binding-Induced DNA Clamp Nanoswitches

Naturally occurring chemoreceptors almost invariably employ structure-switching mechanisms, an observation that has inspired the use of biomolecular switches in a wide range of artificial technologies in the areas of diagnostics, imaging, and synthetic biology. In one mechanism for generating such b...

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Vydáno v:ACS Nano
Hlavní autoři: Idili, Andrea, Plaxco, Kevin W., Vallée-Bélisle, Alexis, Ricci, Francesco
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281346/
https://ncbi.nlm.nih.gov/pubmed/24219761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn404305e
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