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Engineering biosensors with extended, narrowed, or arbitrarily edited dynamic range

Biomolecular recognition has long been an important theme in artificial sensing technologies. A current limitation of protein- and nucleic acid-based recognition, however, is that the useful dynamic range of single-site binding typically spans an 81-fold change in target concentration, an effect tha...

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Autors principals: Vallée-Bélisle, Alexis, Ricci, Francesco, Plaxco, Kevin W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522460/
https://ncbi.nlm.nih.gov/pubmed/22239688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209850j
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