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High-Precision, In Vitro Validation of the Sequestration Mechanism for Generating Ultrasensitive Dose-Response Curves in Regulatory Networks

Our ability to recreate complex biochemical mechanisms in designed, artificial systems provides a stringent test of our understanding of these mechanisms and opens the door to their exploitation in artificial biotechnologies. Motivated by this philosophy, here we have recapitulated in vitro the “tar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ricci, Francesco, Vallée-Bélisle, Alexis, Plaxco, Kevin W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188500/
https://ncbi.nlm.nih.gov/pubmed/21998566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002171
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