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Thermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors
Binding-induced biomolecular switches are used throughout nature and, increasingly, throughout biotechnology for the detection of chemical moieties and the subsequent transduction of this detection into useful outputs. Here we show that the thermodynamics of these switches are quantitatively describ...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728975/ https://ncbi.nlm.nih.gov/pubmed/19666496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904005106 |
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