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Quantification of transcription factor binding in cell extracts using an electrochemical, structure-switching biosensor

Transcription factor expression levels, which sensitively reflect cellular development and disease state, are typically monitored via cumbersome, reagent-intensive assays that require relatively large quantities of cells. Here we demonstrate a simple, quantitative approach to their detection based o...

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Detalhes bibliográficos
Main Authors: Bonham, Andrew J., Hsieh, Kuangwen, Ferguson, B. Scott, Vallée-Bélisle, Alexis, Ricci, Francesco, Soh, H. Tom, Plaxco, Kevin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523731/
https://ncbi.nlm.nih.gov/pubmed/22313286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2115663
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