Characterization of MED12, HMGA2, and FH alterations reveals molecular variability in uterine smooth muscle tumors

Por Mäkinen, Netta, Kämpjärvi, Kati, Frizzell, Norma, Bützow, Ralf, Vahteristo, Pia
Publicado no Mol Cancer (2017)

BACH1 Ser919Pro variant and breast cancer risk

Por Vahteristo, Pia, Yliannala, Kristiina, Tamminen, Anitta, Eerola, Hannaleena, Blomqvist, Carl, Nevanlinna, Heli
Publicado em 2006

MED12 exon 2 mutations in histopathological uterine leiomyoma variants

Por Mäkinen, Netta, Vahteristo, Pia, Kämpjärvi, Kati, Arola, Johanna, Bützow, Ralf, Aaltonen, Lauri A
Publicado em 2013

Rule-based induction method for haplotype comparison and identification of candidate disease loci

Por Karinen, Sirkku, Saarinen, Silva, Lehtonen, Rainer, Rastas, Pasi, Vahteristo, Pia, Aaltonen, Lauri A, Hautaniemi, Sampsa
Publicado em 2012

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12

Por Mäkinen, Netta, Aavikko, Mervi, Heikkinen, Tuomas, Taipale, Minna, Taipale, Jussi, Koivisto-Korander, Riitta, Bützow, Ralf, Vahteristo, Pia
Publicado no PLoS Genet (2016)

Variants on the promoter region of PTEN affect breast cancer progression and patient survival

Por Heikkinen, Tuomas, Greco, Dario, Pelttari, Liisa M, Tommiska, Johanna, Vahteristo, Pia, Heikkilä, Päivi, Blomqvist, Carl, Aittomäki, Kristiina, Nevanlinna, Heli
Publicado em 2011

Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Por Heinonen, Hanna-Riikka, Pasanen, Annukka, Heikinheimo, Oskari, Tanskanen, Tomas, Palin, Kimmo, Tolvanen, Jaana, Vahteristo, Pia, Sjöberg, Jari, Pitkänen, Esa, Bützow, Ralf, Mäkinen, Netta, Aaltonen, Lauri A.
Publicado no Sci Rep (2017)

<it>EPHB2 </it>germline variants in patients with colorectal cancer or hyperplastic polyposis

Por Schleutker Johanna, Eng Charis, Mecklin Jukka-Pekka, Järvinen Heikki, Carvajal-Carmona Luis G, Korja Sanna, Lehtonen Rainer, Laiho Päivi, Kokko Antti, Tomlinson Ian PM, Vahteristo Pia, Aaltonen Lauri A
Publicado em 2006-06-01

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

Por Kokko, Antti, Laiho, Päivi, Lehtonen, Rainer, Korja, Sanna, Carvajal-Carmona, Luis G, Järvinen, Heikki, Mecklin, Jukka-Pekka, Eng, Charis, Schleutker, Johanna, Tomlinson, Ian PM, Vahteristo, Pia, Aaltonen, Lauri A
Publicado em 2006

Nationwide Registry-Based Analysis of Cancer Clustering Detects Strong Familial Occurrence of Kaposi Sarcoma

Por Kaasinen, Eevi, Aavikko, Mervi, Vahteristo, Pia, Patama, Toni, Li, Yilong, Saarinen, Silva, Kilpivaara, Outi, Pitkänen, Esa, Knekt, Paul, Laaksonen, Maarit, Artama, Miia, Lehtonen, Rainer, Aaltonen, Lauri A., Pukkala, Eero
Publicado em 2013

A CHEK2 Genetic Variant Contributing to a Substantial Fraction of Familial Breast Cancer

Por Vahteristo, Pia, Bartkova, Jirina, Eerola, Hannaleena, Syrjäkoski, Kirsi, Ojala, Salla, Kilpivaara, Outi, Tamminen, Anitta, Kononen, Juha, Aittomäki, Kristiina, Heikkilä, Päivi, Holli, Kaija, Blomqvist, Carl, Bartek, Jiri, Kallioniemi, Olli-P., Nevanlinna, Heli
Publicado em 2002

Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers

Por Mehine, Miika, Kaasinen, Eevi, Heinonen, Hanna-Riikka, Mäkinen, Netta, Kämpjärvi, Kati, Sarvilinna, Nanna, Aavikko, Mervi, Vähärautio, Anna, Pasanen, Annukka, Bützow, Ralf, Heikinheimo, Oskari, Sjöberg, Jari, Pitkänen, Esa, Vahteristo, Pia, Aaltonen, Lauri A.
Publicado no Proc Natl Acad Sci U S A (2016)

MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas

Por Kämpjärvi, Kati, Mäkinen, Netta, Mehine, Miika, Välipakka, Salla, Uimari, Outi, Pitkänen, Esa, Heinonen, Hanna-Riikka, Heikkinen, Tuomas, Tolvanen, Jaana, Ahtikoski, Anne, Frizzell, Norma, Sarvilinna, Nanna, Sjöberg, Jari, Bützow, Ralf, Aaltonen, Lauri A, Vahteristo, Pia
Publicado no Br J Cancer (2016)

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia

Por Kämpjärvi, Kati, Järvinen, Tiina M., Heikkinen, Tuomas, Ruppert, Amy S., Senter, Leigha, Hoag, Kevin W., Dufva, Olli, Kontro, Mika, Rassenti, Laura, Hertlein, Erin, Kipps, Thomas J., Porkka, Kimmo, Byrd, John C., de la Chapelle, Albert, Vahteristo, Pia
Publicado no Oncotarget (2014)

Loss of SUFU Function in Familial Multiple Meningioma

Por Aavikko, Mervi, Li, Song-Ping, Saarinen, Silva, Alhopuro, Pia, Kaasinen, Eevi, Morgunova, Ekaterina, Li, Yilong, Vesanen, Kari, Smith, Miriam J., Evans, D. Gareth R., Pöyhönen, Minna, Kiuru, Anne, Auvinen, Anssi, Aaltonen, Lauri A., Taipale, Jussi, Vahteristo, Pia
Publicado em 2012

Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer

Por Gylfe, Alexandra E., Katainen, Riku, Kondelin, Johanna, Tanskanen, Tomas, Cajuso, Tatiana, Hänninen, Ulrika, Taipale, Jussi, Taipale, Minna, Renkonen-Sinisalo, Laura, Järvinen, Heikki, Mecklin, Jukka-Pekka, Kilpivaara, Outi, Pitkänen, Esa, Vahteristo, Pia, Tuupanen, Sari, Karhu, Auli, Aaltonen, Lauri A.
Publicado em 2013

ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancer

Por Siltanen, Sanna, Syrjäkoski, Kirsi, Fagerholm, Rainer, Ikonen, Tarja, Lipman, Peter, Mallott, Jacob, Holli, Kaija, Tammela, Teuvo LJ, Järvinen, Heikki J, Mecklin, Jukka-Pekka, Aittomäki, Kristiina, Blomqvist, Carl, Bailey-Wilson, Joan E, Nevanlinna, Heli, Aaltonen, Lauri A, Schleutker, Johanna, Vahteristo, Pia
Publicado em 2008

Uterine leiomyoma-linked MED12 mutations disrupt Mediator-associated CDK activity

Por Turunen, Mikko, Spaeth, Jason M., Keskitalo, Salla, Park, Min Ju, Kivioja, Teemu, Clark, Alison D., Mäkinen, Netta, Gao, Fangjian, Palin, Kimmo, Nurkkala, Helka, Vähärautio, Anna, Aavikko, Mervi, Kämpjärvi, Kati, Vahteristo, Pia, Kim, Chongwoo A., Aaltonen, Lauri A., Varjosalo, Markku, Taipale, Jussi, Boyer, Thomas G.
Publicado em 2014

Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations

Por Georgitsi, Marianthi, Raitila, Anniina, Karhu, Auli, Tuppurainen, Karoliina, Mäkinen, Markus J., Vierimaa, Outi, Paschke, Ralf, Saeger, Wolfgang, van der Luijt, Rob B., Sane, Timo, Robledo, Mercedes, De Menis, Ernesto, Weil, Robert J., Wasik, Anna, Zielinski, Grzegorz, Lucewicz, Olga, Lubinski, Jan, Launonen, Virpi, Vahteristo, Pia, Aaltonen, Lauri A.
Publicado em 2007