Mutations in normal breast tissue and breast tumours

Por Tomlinson, Ian PM
Publicado em 2001

The FH mutation database: an online database of fumarate hydratase mutations involved in the MCUL (HLRCC) tumor syndrome and congenital fumarase deficiency

Por Bayley, Jean-Pierre, Launonen, Virpi, Tomlinson, Ian PM
Publicado em 2008

Whole-genome methylation analysis of benign and malignant colorectal tumours

Por Beggs, Andrew D, Jones, Angela, El-Bahwary, Mona, Abulafi, Muti, Hodgson, Shirley V, Tomlinson, Ian PM
Publicado em 2013

MED12 exon 2 mutations are common in uterine leiomyomas from South African patients

Por Mäkinen, Netta, Heinonen, Hanna-Riikka, Moore, Shane, Tomlinson, Ian P.M., van der Spuy, Zephne M., Aaltonen, Lauri A.
Publicado em 2011

Methylation changes in the TFAP2E promoter region are associated with BRAF mutation and poorer overall & disease free survival in colorectal cancer

Por Beggs, Andrew D., Dilworth, Mark P., Domingo, Enric, Midgley, Rachel, Kerr, David, Tomlinson, Ian P.M., Middleton, Gary W.
Publicado no Oncoscience (2015)

Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci

Por Niittymäki, Iina, Tuupanen, Sari, Li, Yilong, Järvinen, Heikki, Mecklin, Jukka-Pekka, Tomlinson, Ian PM, Houlston, Richard S, Karhu, Auli, Aaltonen, Lauri A
Publicado em 2011

Low-Penetrance Susceptibility Variants in Familial Colorectal Cancer

Por Niittymäki, Iina, Kaasinen, Eevi, Tuupanen, Sari, Karhu, Auli, Järvinen, Heikki, Mecklin, Jukka-Pekka, Tomlinson, Ian P.M., Di Bernardo, Maria Chiara, Houlston, Richard S., Aaltonen, Lauri A.
Publicado em 2010

<it>EPHB2 </it>germline variants in patients with colorectal cancer or hyperplastic polyposis

Por Schleutker Johanna, Eng Charis, Mecklin Jukka-Pekka, Järvinen Heikki, Carvajal-Carmona Luis G, Korja Sanna, Lehtonen Rainer, Laiho Päivi, Kokko Antti, Tomlinson Ian PM, Vahteristo Pia, Aaltonen Lauri A
Publicado em 2006-06-01

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

Por Kokko, Antti, Laiho, Päivi, Lehtonen, Rainer, Korja, Sanna, Carvajal-Carmona, Luis G, Järvinen, Heikki, Mecklin, Jukka-Pekka, Eng, Charis, Schleutker, Johanna, Tomlinson, Ian PM, Vahteristo, Pia, Aaltonen, Lauri A
Publicado em 2006

Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN

Por Beggs, Andrew D, Domingo, Enric, McGregor, Megan, Presz, Mikael, Johnstone, Elaine, Midgley, Rachel, Kerr, David, Oukrif, Dahmane, Novelli, Marco, Abulafi, Muti, Hodgson, Shirley V, Fadhil, Wakkas, Ilyas, Mohammad, Tomlinson, Ian PM
Publicado em 2012

DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer

Por Church, David N., Briggs, Sarah E.W., Palles, Claire, Domingo, Enric, Kearsey, Stephen J., Grimes, Jonathon M., Gorman, Maggie, Martin, Lynn, Howarth, Kimberley M., Hodgson, Shirley V., Kaur, Kulvinder, Taylor, Jenny, Tomlinson, Ian P.M.
Publicado em 2013

DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers

Por Jorissen, Robert N., Lipton, Lara, Gibbs, Peter, Chapman, Matthew, Desai, Jayesh, Jones, Ian T., Yeatman, Timothy J., East, Philip, Tomlinson, Ian P.M., Verspaget, Hein W., Aaltonen, Lauri A., Kruhøffer, Mogens, Ørntoft, Torben F., Andersen, Claus Lindbjerg, Sieber, Oliver M.
Publicado em 2008

POLE proofreading mutations elicit an anti-tumor immune response in endometrial cancer

Por van Gool, Inge C, Eggink, Florine A, Freeman-Mills, Luke, Stelloo, Ellen, Marchi, Emanuele, de Bruyn, Marco, Palles, Claire, Nout, Remi A, de Kroon, Cor D, Osse, Elisabeth M, Klenerman, Paul, Creutzberg, Carien L, Tomlinson, Ian PM, Smit, Vincent THBM, Nijman, Hans W, Bosse, Tjalling, Church, David N
Publicado no Clin Cancer Res (2015)

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

Por Spain, Sarah L., Carvajal-Carmona, Luis G., Howarth, Kimberley M., Jones, Angela M., Su, Zhan, Cazier, Jean-Baptiste, Williams, Jennet, Aaltonen, Lauri A., Pharoah, Paul, Kerr, David J., Cheadle, Jeremy, Li, Li, Casey, Graham, Vodicka, Pavel, Sieber, Oliver, Lipton, Lara, Gibbs, Peter, Martin, Nicholas G., Montgomery, Grant W., Young, Joanne, Baird, Paul N., Morreau, Hans, van Wezel, Tom, Ruiz-Ponte, Clara, Fernandez-Rozadilla, Ceres, Carracedo, Angel, Castells, Antoni, Castellvi-Bel, Sergi, Dunlop, Malcolm, Houlston, Richard S., Tomlinson, Ian P.M.
Publicado em 2012

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Por Houlston, Richard S, Cheadle, Jeremy, Dobbins, Sara E, Tenesa, Albert, Jones, Angela M, Howarth, Kimberley, Spain, Sarah L, Broderick, Peter, Domingo, Enric, Farrington, Susan, Prendergast, James GD, Pittman, Alan M, Theodoratou, Evi, Smith, Christopher G, Olver, Bianca, Walther, Axel, Barnetson, Rebecca A, Churchman, Michael, Jaeger, Emma EM, Penegar, Steven, Barclay, Ella, Martin, Lynn, Gorman, Maggie, Mager, Rachel, Johnstone, Elaine, Midgley, Rachel, Niittymäki, Iina, Tuupanen, Sari, Colley, James, Idziaszczyk, Shelley, Thomas, Huw JM, Lucassen, Anneke M, Evans, D Gareth R, Maher, Eamonn R, Maughan, Timothy, Dimas, Antigone, Dermitzakis, Emmanouil, Cazier, Jean-Baptiste, Aaltonen, Lauri A, Pharoah, Paul, Kerr, David J, Carvajal-Carmona, Luis G, Campbell, Harry, Dunlop, Malcolm G, Tomlinson, Ian PM
Publicado no Nat Genet (2010)

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

Por Tenesa, Albert, Farrington, Susan M, Prendergast, James GD, Porteous, Mary E, Walker, Marion, Haq, Naila, Barnetson, Rebecca A, Theodoratou, Evropi, Cetnarskyj, Roseanne, Cartwright, Nicola, Semple, Colin, Clark, Andrew J, Reid, Fiona JL, Smith, Lorna A, Kavoussanakis, Kostas, Koessler, Thibaud, Pharoah, Paul DP, Buch, Stephan, Schafmayer, Clemens, Tepel, Jürgen, Schreiber, Stefan, Völzke, Henry, Schmidt, Carsten O, Hampe, Jochen, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Wilkening, Stefan, Canzian, Federico, Capella, Gabriel, Moreno, Victor, Deary, Ian J, Starr, John M, Tomlinson, Ian PM, Kemp, Zoe, Howarth, Kimberley, Carvajal-Carmona, Luis, Webb, Emily, Broderick, Peter, Vijayakrishnan, Jayaram, Houlston, Richard S, Rennert, Gad, Ballinger, Dennis, Rozek, Laura, Gruber, Stephen B, Matsuda, Koichi, Kidokoro, Tomohide, Nakamura, Yusuke, Zanke, Brent W, Greenwood, Celia MT, Rangrej, Jagadish, Kustra, Rafal, Montpetit, Alexandre, Hudson, Thomas J, Gallinger, Steven, Campbell, Harry, Dunlop, Malcolm G
Publicado em 2008

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk

Por Guo, Xingyi, Long, Jirong, Zeng, Chenjie, Michailidou, Kyriaki, Ghoussaini, Maya, Bolla, Manjeet K., Wang, Qin, Milne, Roger L., Shu, Xiao-Ou, Cai, Qiuyin, Beesley, Jonathan, Kar, Siddhartha P., Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Beckmann, Matthias W., Beeghly-Fadiel, Alicia, Benitez, Javier, Blot, William, Bogdanova, Natalia, Bojesen, Stig E., Brauch, Hiltrud, Brenner, Hermann, Brinton, Louise, Broeks, Annegien, Brüning, Thomas, Burwinkel, Barbara, Cai, Hui, Canisius, Sander, Chang-Claude, Jenny, Choi, Ji-Yeob, Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Darabi, Hatef, Devilee, Peter, Droit, Arnaud, Dörk, Thilo, Fasching, Peter A., Fletcher, Olivia, Flyger, Henrik, Fostira, Florentia, Gaborieau, Valerie, García-Closas, Montserrat, Giles, Graham G., Grip, Mervi, Guénel, Pascal, Haiman, Christopher A., Hamann, Ute, Hartman, Mikael, Hollestelle, Antoinette, Hopper, John L., Hsiung, Chia-Ni, Ito, Hidemi, Jakubowska, Anna, Johnson, Nichola, Kabisch, Maria, Kang, Daehee, Khan, Sofia, Knight, Julia A., Kosma, Veli-Matti, Lambrechts, Diether, Marchand, Loic Le, Li, Jingmei, Lindblom, Annika, Lophatananon, Artitaya, Lubinski, Jan, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Marme, Frederik, Matsuo, Keitaro, McLean, Catriona A., Meindl, Alfons, Muir, Kenneth, Neuhausen, Susan L., Nevanlinna, Heli, Nord, Silje, Olson, Janet E., Orr, Nick, Peterlongo, Paolo, Putti, Thomas Choudary, Rudolph, Anja, Sangrajrang, Suleeporn, Sawyer, Elinor J., Schmidt, Marjanka K., Schmutzler, Rita K., Shen, Chen-Yang, Shi, Jiajun, Shrubsole, Martha J, Southey, Melissa C., Swerdlow, Anthony, Teo, Soo Hwang, Thienpont, Bernard, Toland, Amanda Ewart, Tollenaar, Robert A.E.M., Tomlinson, Ian P.M., Truong, Thérèse, Tseng, Chiu-chen, van den Ouweland, Ans, Wen, Wanqing, Winqvist, Robert, Wu, Anna, Yip, Cheng Har, Zamora, M. Pilar, Zheng, Ying, Hall, Per, Pharoah, Paul D.P., Simard, Jacques, Chenevix-Trench, Georgia, Dunning, Alison M., Easton, Douglas F., Zheng, Wei
Publicado no Cancer Epidemiol Biomarkers Prev (2015)