Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN

Repair of double strand DNA breaks (DSBs) is pivotal in maintaining normal cell division and disruption of this system has been shown to be a key factor in carcinogenesis. Loss of expression of the DSB repair proteins have previously been shown to be associated with poorer survival in colorectal can...

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Autores principales: Beggs, Andrew D, Domingo, Enric, McGregor, Megan, Presz, Mikael, Johnstone, Elaine, Midgley, Rachel, Kerr, David, Oukrif, Dahmane, Novelli, Marco, Abulafi, Muti, Hodgson, Shirley V, Fadhil, Wakkas, Ilyas, Mohammad, Tomlinson, Ian PM
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717797/
https://ncbi.nlm.nih.gov/pubmed/23154512
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