DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer

Accurate duplication of DNA prior to cell division is essential to suppress mutagenesis and tumour development. The high fidelity of eukaryotic DNA replication is due to a combination of accurate incorporation of nucleotides into the nascent DNA strand by DNA polymerases, the recognition and removal...

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Autors principals: Church, David N., Briggs, Sarah E.W., Palles, Claire, Domingo, Enric, Kearsey, Stephen J., Grimes, Jonathon M., Gorman, Maggie, Martin, Lynn, Howarth, Kimberley M., Hodgson, Shirley V., Kaur, Kulvinder, Taylor, Jenny, Tomlinson, Ian P.M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690967/
https://ncbi.nlm.nih.gov/pubmed/23528559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt131
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