The Multiple Biological Roles of the 3′→5′ Exonuclease of Saccharomyces cerevisiae DNA Polymerase δ Require Switching between the Polymerase and Exonuclease Domains

Until recently, the only biological function attributed to the 3′→5′ exonuclease activity of DNA polymerases was proofreading of replication errors. Based on genetic and biochemical analysis of the 3′→5′ exonuclease of yeast DNA polymerase δ (Pol δ) we have discerned additional biological roles for...

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Main Authors: Jin, Yong Hwan, Garg, Parie, Stith, Carrie M. W., Al-Refai, Hanan, Sterling, Joan F., Murray, Laura J. W., Kunkel, Thomas A., Resnick, Michael A., Burgers, Peter M., Gordenin, Dmitry A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538786/
https://ncbi.nlm.nih.gov/pubmed/15601866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.461-471.2005
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