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Inefficient Proofreading and Biased Error Rates during Inaccurate DNA Synthesis by a Mutant Derivative of Saccharomyces cerevisiae DNA Polymerase δ

DNA polymerase δ (pol δ) is a high fidelity eukaryotic enzyme that participates in DNA repair and is essential for DNA replication. Toward the goal of dissecting its multiple biological functions, here we describe the biochemical properties of Saccharomyces cerevisiae pol δ with a methionine replaci...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Nick McElhinny, Stephanie A., Stith, Carrie M., Burgers, Peter M. J., Kunkel, Thomas A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2006
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839876/
https://ncbi.nlm.nih.gov/pubmed/17121822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609591200
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