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Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ε
We have investigated the ability of the 3′ exonuclease activity of S. cerevisiae DNA polymerase ε (Pol ε) to proofread newly inserted ribonucleotides (rNMPs). During DNA synthesis in vitro, Pol ε proofreads ribonucleotides with apparent efficiencies that vary from none at some locations to more than...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407341/ https://ncbi.nlm.nih.gov/pubmed/22682724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.05.004 |
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