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Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases

The major replicative DNA polymerases of S. cerevisiae (Pols α, δ, and ε) incorporate substantial numbers of ribonucleotides into DNA during DNA synthesis. When these ribonucleotides are not removed in vivo, they reside in the template strand used for the next round of replication and could potentia...

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Main Authors: Watt, Danielle L., Johansson, Erik, Burgers, Peter M., Kunkel, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147116/
https://ncbi.nlm.nih.gov/pubmed/21703943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.05.009
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