Proficient Replication of the Yeast Genome by a Viral DNA Polymerase

DNA replication in eukaryotic cells requires minimally three B-family DNA polymerases: Pol α, Pol δ, and Pol ϵ. Pol δ replicates and matures Okazaki fragments on the lagging strand of the replication fork. Saccharomyces cerevisiae Pol δ is a three-subunit enzyme (Pol3-Pol31-Pol32). A small C-termina...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Stodola, Joseph L., Stith, Carrie M., Burgers, Peter M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
DNA and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882438/
https://ncbi.nlm.nih.gov/pubmed/27072134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.728741
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